Vascular

Abdominal Aortic Aneurysm (AAA)

PATHO

  • Localized dilation of ABD aorta > 1.5 x normal diameter (~2 cm) but > 3 cm ➔ dx of aneurysm

  • ↑ risk of thrombus

  • > 5 cm ➔ ↑ risk of rupture

  • RF: ♂> ♀, atherosclerosis/↑ cholesterol, smoking, ↑ age, family hx, C.T. dzs (marfan), hx of aortic graft (hx of dissection)

    • Atherosclerosis ➔ inflammation ➔ proteases degrade tunica media ➔ weak aorta

    • Below renal arteries (infra renal) MC because ABD aorta doesn't have vasculature that feeds aorta (like it does higher up)

SSX

  • Incidental finding and ASX or... ABD/low back pain, flank pain/renal colic (can mimic kidney stone sx)

  • Palpable ABD mass (may be pulsating), ABD bruit

  • Hypotension/syncope and ecchymotic flank means they ruptured

  • Retroperitoneal bleeding (associated with hemorrhagic pancreatitis or AAA)

    • Grey turner sign - flank ecchymoses (Turn them on their side and they're grey)

    • Cullen sign - peri-umbilical ecchymoses (cUllen - umbilical)

  • Aorta-enteric fistula ➔ acute GI bleed presentation with hx of aorta repair

  • Rupture into IVC or iliac veins ➔ acute venous HTN ➔ ruptured bladder vessels ➔ hematuria

Screening

  • ABD US

    • ♂ smoking hx 65-75yo (consider in ♂ & ♀ 65-75 yo with family hx)

      • > 2.5 cm - 2.9 cm: US q 10yr

      • AAA 3.0 - 3.9 cm: US q 3yrs

      • AAA 4.0 - 4.9 cm: US q 1yr

      • AAA 5.0 - 5.4 cm: US q 6mo

DX

  • AAA suspected but no sx ABD US (usually... best initial and confirmatory test)

  • Pt has sx but is stable CT with IV contrast or angiography

  • Pt is sick (rupture) ➔ surgery within 90 mins

    • Can do focused bedside US in non-obese pts but don't delay tx if presentation says ruptured/pending rupture

TX

  • 3.0 cm - 5.4 cm ➔ β-blockers, smoking cessation, repeat US (intervals determined by size)

  • Surgery - Immediate Endovascular repair (EVAR) > open surgical repair (OSR)

    • Unstable pt (rupture)

    • > 5.5 cm or ↑ diameter of 0.5 cm