Venous return (input)
Blood making it into right atrium
More coming in means more can go out...
less coming in means less can go out...
Constricting veins ➔ ↑ venous resistance ➔ ↓ venous return
Denominator goes to 2
BUT with sympathetic stimulation/exercise:
Venous pressure (BP) ↑ to overcome constriction ➔ ↑ venous return
Breathing in ➔ diaphragm moves down ➔ expanded lungs & thoracic cavity
↓ intra-thoracic pressure ➔ ↓ RA pressure ➔ ↑ venous return
I think of it like a deep breath moves lungs away from my heart and vena cava
Makes it easier for blood to dump into RA via SVC
Diaphragm moving down ➔ ↑ intra-abdominal pressure (transient)
↑ ABD pressure with ↓ thoracic pressure shoots blood coming up IVC into RA
Blood pools in expanded lungs ➔ ↓ LEFT SIDED PRELOAD
Valsalva: if you tighten your ABD muscles you ↑ ABD pressure
When you bear down and hold that valsalva ➔ ↑ venous resistance ➔ ↓ venous return
Unlike the transient ↑ in venous return that happens when ABD pressure ↑'s during inspiration
Less blood in the heart means less blood to push out and make noise in left side*
It is easier for blood to get to the heart when it doesn’t have to work against gravity
Squatting brings legs closer to heart but it also can ↑ afterload
Resistance to getting blood out of the left means:
More regurgitation in AR and MR ➔ ↑ murmur
More L ➔ R in VSD ➔ ↑ murmur
Less blood on left (↓ L preload) means more obstruction ➔ ↑ murmur intensity
PHYSIOLOGICAL SPLIT OF S2 (normal finding with inspiration)
Aortic valve (A2) closes then pulmonary valve (P2)
Blood pooling in pulmonary circulation ➔ shortened LV systole ➔ early aortic valve closure (A2)
↑ venous return right side ➔ prolonged RV systole ➔ late pulmonary valve closure (P2)
WIDE SPLIT
More pronounced during inspiration (A2 then P2)
↑ RV afterload ➔ prolonged RV systole or ↓ LV preload ➔ shortened LV systole
Pulmonary HTN, pulmonary stenosis, Severe MR, WPW, Constrictive pericarditis, RBBB
FIXED SPLIT
Doesn’t ∆ with inspiration (always there)
ASD: Communication between R and L negates pressure ∆ that occur with inspiration
PARADOXICAL SPLIT
Audible during expiration but not inspiration
HOCM, AS